Verb | 1. | louse up - make a mess of, destroy or ruin; "I botched the dinner and we had to eat out"; "the pianist screwed up the difficult passage in the second movement"Synonyms: bobble, bollix, bollix up, bollocks, bollocks up, botch, botch up, bumble, bungle, flub, fluff, foul up, fuck up, mess up, mishandle, muck up, ball up, spoil, muff, screw up, fumble, blow |