| n. | 1. | (Med.) originally, a cutaneous disease with the appearance of the skin having been gnawed, and occurring under two distinct forms. Now used as a generic term for over ten distinguishable diseases having visible cutaneous symptoms. |
| 2. | (Astron.) The Wolf, a constellation situated south of Scorpio. |
| Noun | 1. | lupus - any of several forms of ulcerative skin disease |
| 2. | Lupus - a constellation in the southern hemisphere near Centaurus |